Download Drug and Enzyme Targeting: Part A by Nathan P. Colowick, Nathan P. Kaplan, Kenneth J. Widder, PDF

By Nathan P. Colowick, Nathan P. Kaplan, Kenneth J. Widder, Ralph Green

The significantly acclaimed laboratory average, equipment in Enzymology, is without doubt one of the such a lot hugely revered courses within the box of biochemistry. on account that 1955, each one quantity has been eagerly awaited, often consulted, and praised by way of researchers and reviewers alike. The sequence includes a lot fabric nonetheless suitable this day - actually a vital book for researchers in all fields of lifestyles sciences.

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Millar, L. McMillan, W. J. Hannan, P. C. Emmett, and R. J. Aitken, Int. J. Appl. Radiat. Isot. 33, 1423 (1982). , free-flowing, freeze-dried powder) " From ref. 5. purified olive oil (125 ml) is added to a flat-bottomed glass beaker (diameter 60 mm, height 110 mm) equipped with four baffles (4 mm depth) positioned against the wall of the beaker. A motor-driven four-bladed axial-flow impeller is placed in the center of the beaker, two-thirds into the oil, such that there is a distance of 3 mm between the baffles and the impeller blade.

5 K. 6 H. R h o d e s , I. Zolle, J. B u c h a n a n , and H. Wagner, Radiology 92, 1453 (1969). K r a m e r , J. Pharm. Sci. 63, 1646 (1976). Lee, T. Sokoloski, and G. Royer, Science 213, 4503 (1982). Senyei, S. Reich, C. Gonczy, and K. Widder, J. Pharm. Sci. 70, 328 (1981L Widder, A. Senyei, and D. R a n n e y , Cancer Res. 40, 3512 (1980). Kimelberg, Mol. Cell. Biochem. 10, 171 (1976). METHODS IN ENZYMOLOGY,VOL. 112 Copyright © 1985by AcademicPress. Inc. All rights of reproduction in any form reserved.

Inc. All rights of reproduction in any form reserved. ISBN 0-12-182012-2 18 MICROENCAPSULAT1ON TECHNIQUES [2] methods for using magnetic albumin microspheres in targeted drug delivery applications have likewise been described in considerable detail by Senyei and Widder. 23-25 Additional discussion of this subject material is presented elsewhere in this volume. 26 23 K. J. Widder and A. E. S. Patent 4,247,406 (1981). 24 A. E. Senyei and K. J. S. Patent 4,357,259, to Northwestern University (1982).

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